High CyPA expression in non-small cell lung cancer and its relationship with clinical pathological characteristics / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 146-149, 2010.
Article
em Zh
| WPRIM
| ID: wpr-840939
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To investigate the expression and distribution of CyPA in non-small cell lung cancer (NSCLC) and to evaluate its clinical significance in the development and progression of NSCLC. Methods: The expression of CyPA was examined in 45 NSCLC tissues, 22 paired tumor-adjacent tissues and 33 normal pulmonary tissues using tissue microarray immunohistochemistry method. The relationship between CyPA expression in NSCLC and clinic pathological characteristics of NSCLC was analyzed. Results: Expression of CyPA in NSCLC tissues and paired tumor-adjacent tissues was significantly higher than that in the normal pulmonary tissues (P<0.05). No significant correlation was found between the expression of CyPA and differentiation and histological types of NSCLC. Conclusion: CyPA is overexpressed in NSCLC tissues, suggesting that CyPA might serve as a biomarker for the development and progression of NSCLC, whose specific role remains to be further studied.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
2010
Tipo de documento:
Article