Role of angiotensin- II in cell apoptosis / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 1368-1371, 2010.
Article
em Zh
| WPRIM
| ID: wpr-841258
Biblioteca responsável:
WPRO
ABSTRACT
Angiotensin-II-induced apoptosis was widely involved in the pathogenesis of diabetes mellitus, cardiovascular diseases, etc. The mechanism of angiotensin-II-induced apoptosis is complicated, including the receptor (AT1R and AT2R) level regulation, Fas/FasL pathway, and the regulation by p53 family, Bcl-2 family, Caspase family, Ang-(1-7), etc. Mitochondria damage and oxidative damage play important roles in the apoptosis process. This article reviews the previous researches on angiotensin-II-induced apoptosis.
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WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
2010
Tipo de documento:
Article