Studies on the chemical constituents of Bidens bipinnata L / 第二军医大学学报

ABSTRACT

Objective: To investigate the bioactive chemical constituents in Bidens bipinnata L. for treatment of diabetes. Methods: Extraction was done with 80% EtOH; isolation and purification were carried out on silica gel, C18 silica gel column, and Sephadex-LH2O column; and the chemical structures of the products were identified by physicochemical properties and spectral analysis. Results: Nine compounds were obtained from Bidens bipinnata L. and their chemical structures were identified as quercitin(I), hyperoside (II),quercitin-7-O-rhamnopyranoside(III), 6,7,3′4′-tetrahydroxy aurone(IV),4,5-di-O- caffeoyl quinic acid(V), stigmasterol 3-O-glucopyranoside (VI),ethyl 3,4-dihydroxybenzoate(VII), okanin(VII),and luteolin(IX). Conclusion: Except for okanin and hyperoside, the rest 7 compounds are isolated from the plant for the first time.