Cardiovascular risk factors of early atherosclerosis in school-aged children after Kawasaki disease / 소아과
Korean Journal of Pediatrics
;
: 217-221, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-84219
ABSTRACT
PURPOSE:
The aim of this study was to determine whether school-aged children with Kawasaki disease (KD) have an increased risk for early atherosclerosis.METHODS:
The study included 98 children. The children were divided into the following groups group A (n=19), KD with coronary arterial lesions that persisted or regressed; group B (n=49), KD without coronary arterial lesions; and group C (n=30), healthy children. Anthropometric variables and the levels of biochemical markers, including total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein A, apolipoprotein B, homocysteine, high-sensitivity C-reactive protein (hs-CRP), and brachial artery stiffness using pulse wave velocity were compared among the three groups.RESULTS:
There were no significant differences in blood pressure and body index among the three groups. Additionally, there was no sex-specific difference. Moreover, the levels of triglyceride, HDL-C, apolipoprotein A, and hs-CRP did not differ among the three groups. However, the levels of total cholesterol (P=0.018), LDL-C (P=0.0003), and apolipoprotein B (P=0.029) were significantly higher in group A than in group C. Further, the level of homocysteine and the aortic pulse wave velocity were significantly higher in groups A and B than in group C (P=0.0001).CONCLUSION:
School-aged children after KD have high lipid profiles and arterial stiffness indicating an increased risk for early atherosclerosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Apolipoproteínas
/
Triglicerídeos
/
Pressão Sanguínea
/
Artéria Braquial
/
Proteína C-Reativa
/
Biomarcadores
/
Colesterol
/
Fatores de Risco
/
Aterosclerose
/
Rigidez Vascular
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2014
Tipo de documento:
Artigo
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