Effect of RNA N6-methyladenosine on immunoregulation / 上海交通大学学报(医学版)
Journal of Shanghai Jiaotong University(Medical Science)
;
(12): 534-538, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-843227
ABSTRACT
N6-methyladenosine (m6A) is the most prevalent and abundant post-transcriptional RNA modification in eukaryotes. m6A is a dy-namic and reversible process catalyzed by m6A methyltransferase complex and demethylase. m6A is involved in the regulations of gene expres-sion and biological processes. Recently, researches have discovered that m6A plays a vital role in the differentiation and regulation of immune cells, which could provide a new idea for the research and therapy of immune-related diseases. The present article reviews the recent progresses of m6A in immunoregulation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Shanghai Jiaotong University(Medical Science)
Ano de publicação:
2020
Tipo de documento:
Artigo
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