The Association between Albuminuria and Peripheral Arterial Disease in Patients with Type 2 Diabetes Mellitus / 대한내과학회지
Korean Journal of Medicine
;
: 73-81, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-84333
ABSTRACT
BACKGROUND/AIMS:
Albuminuria is an early indicator of renal damage in type 2 diabetes mellitus, and has been recognized as a risk factor for peripheral arterial disease (PAD). The aim of this study was to assess the association between albuminuria and PAD in Korean type 2 diabetes patients.METHODS:
Our retrospective study included 390 consecutive patients with type 2 diabetes mellitus. The ankle-brachial index (ABI) and toe-brachial index (TBI) were used to assess PAD. The urinary albumin-creatinine excretion ratio (UAE) was evaluated by determining the albumin/creatinine ratio (ACR) in the first voided morning urine sample.RESULTS:
Duration of diabetes, serum creatinine levels, and UAE were significantly higher in patients with low ABI scores ( or = 0.9). Age, duration of diabetes, and UAE were significantly higher in patients with low TBI scores ( or = 0.6). Albuminuria was independently associated with low ABI (OR = 1.980, 95% CI = 1.001-3.918). It was also independently associated with low TBI and normal ABI (OR = 3.149, 95% CI = 1.260-7.871).CONCLUSIONS:
The results of this study suggest that albuminuria may be associated with PAD, including in arteries distal to the ankle joint.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artérias
/
Estudos Retrospectivos
/
Fatores de Risco
/
Doenças Vasculares Periféricas
/
Creatinina
/
Diabetes Mellitus
/
Diabetes Mellitus Tipo 2
/
Albuminúria
/
Índice Tornozelo-Braço
/
Doença Arterial Periférica
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2011
Tipo de documento:
Artigo
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