Advances of pathogenesis and clinical research in anti-N-methyl-D-aspartate receptor encephalitis / 上海交通大学学报（医学版）

ABSTRACT

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is one kind of autoimmune encephalitis that is mediated by NMDAR antibodies. Most of the patients are young women and some of them may suffer from tumors. Diagnosis is mainly based on identification of NMDAR antibodies in cerebrospinal fluid and serum. Most patients can recover after removal of the tumor or through immunotherapy. This article reviews some viewpoints of pathogenesis, genetic features, clinical characteristics, treatment and prognosis of the disease.