Clinical observation on prevention of pterygium recurrence with bleomycin in pterygium surgery / 上海交通大学学报（医学版）

ABSTRACT

Objective • To observe the clinical effect of bleomycin for prevention of recurrence after pterygium treatment. Methods • Pterygium excision surgery combined with conjunctival autograft transplantation method on 59 patients (82 eyes) was performed, bleomycin (3 mg/mL) was used to prevent recurrence during the surgery. Corneal and conjunctival wound healing, recurrence rate and complications were observed in all the patients after surgery. Results • All the patients were followed-up for 6 months or more [(18.5±9.7) months]. After surgery, the corneas were transparent; the conjunctival flaps healed well and fused with surrounding tissues; no obvious scar hyperplasia and no recurrence of pterygium occured during the follow-up. None of the patients had sustained corneal epithelial defect, scleral ischemia, symblepharon, secondary glaucoma or cataract. Conclusion • The application of bleomycin may reduce the recurrence rate of pterygium effectively without serious complications.