Application of mechanical thrombectomy in the patients with wake-up stroke / 上海交通大学学报（医学版）

ABSTRACT

Wake-up stroke (WUS), which is characterized by the uncertain onset time and poor short-term outcome, accounts for 25% of stroke. Due to the above two points, how to choose the treatment methods remains to be researched. The mechanical thrombectomy is the first-line treatment of acute ischemic stroke (AIS). DAWN and DEFUSE-3 studies have recently demonstrated that the treatment window can be expanded to 24 hours, so the endovascular treatment may be effective and safe in some WUS patients according to the existence of "the mismatch of clinical score and imaging infart core" by CT perfusion imaging and other modern imaging methods. This article summarized the application of mechanical thrombectomy in WUS treatment in recent years.