Neuroimaging advances in the studies on cognitive dysfunction in patients with end-stage renal disease / 西安交通大学学报(医学版)

ABSTRACT

End-stage renal disease (ESRD) is the serious outcome of chronic kidney disease. ESRD patients need dialysis or kidney transplantation to sustain life. According to epidemiological investigations, ESRD patients generally have cognitive dysfunction, which is one of the key problems affecting patients' quality of life. In this paper, the potential relationship among ESRD, brain structure and function, and cognitive function is described based on magnetic resonance imaging technology in ESRD patients. This paper points out that the key problem to be solved is to predict cognitive outcome based on imaging markers.