An efficient and impartial online algorithm for kidney assignment network / 西安交通大学学报·英文版

ABSTRACT

An online algorithm balancing the efficiency and equity principles is proposed for the kidney resource assignment when only the current patient and resource information is known to the assignment network. In the algorithm, the assignment is made according to the priority, which is calculated according to the efficiency principle and the equity principle. The efficiency principle is concerned with the post-transplantation' immunity spending caused by the possible post-operation immunity rejection and patient's mental depression due to the HLA mismatch. The equity principle is concerned with three other factors, namely the treatment spending incurred starting from the day of registering with the kidney assignment network, the post-operation immunity spending and the negative effects of waiting for kidney resources on the clinical efficiency. The competitive analysis conducted through computer simulation indicates that the efficiency competitive ratio is between 6.29 and 10.43 and the equity competitive ratio is between 1. 31 and 5.21, demonstrating that the online algorithm is of great significance in application.