Organic cation transporters in central nervous system diseases: research advances / 国际药学研究杂志
Journal of International Pharmaceutical Research
;
(6): 594-601, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-845139
ABSTRACT
Organic cation transporters(OCT), one of the important members of membrane transporter family, can transport many kinds of positively charged substances and organic cation drugs used in physiological and pharmacological researches. A large number of studies have shown that the expression and function of OCT play an important role in the pathogenesis of some central nervous system(CNS)diseases, thus affecting the homeostasis of the internal environment. This article reviews the structure, substrate selectivity, tissue distribution and gene polymorphism of OCT in the CNS and provides a new possibility for the development of drugs targeting OCT and the clinical targeting of CNS diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of International Pharmaceutical Research
Ano de publicação:
2020
Tipo de documento:
Artigo
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