Quantitative evaluation of baicalin Radix Scutellariae granules by near-infrared spectroscopy / 国际药学研究杂志
Journal of International Pharmaceutical Research
; (6): 466-469, 2017.
Article
em Zh
| WPRIM
| ID: wpr-845372
Biblioteca responsável:
WPRO
ABSTRACT
Objective To determine the content of baicalin in Radix Scutellariae granule from different manufacturers using near infrared spectroscopy(NIRS)technology. Methods Utilizing NIRS combined with partial least squares, and simultaneously optimizing the pretreatment methods and the range of spectrum, the quantitative model of baicalin in Radix Scutellarie granules was established. Results In the model correlation coefficient(R2)was 0.9702, root-mean-square error of calibration(RMSEC)was 0.555, and root-mean-square error of predict(RMSEP)was 1.05. Conclusion In this paper, rapid quality analysis method of Radix Scutellariae granules from different manufacturers is studied using NIRS technology. The model can predict the content of baicalin nondestructively and rapidly. It can give some reference for researching the quality control of Radix Scutellariae granules.
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Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of International Pharmaceutical Research
Ano de publicação:
2017
Tipo de documento:
Article