Roles and functional changes of astrocytes in diabetic brain encephalopathy / 国际药学研究杂志

ABSTRACT

Diabetes mellitus can cause central nervous system disorder that is summarized as diabetic encephalopathy, which manifests in cognitive dysfunction and other mental illnesses. Astrocyte, with a huge number and extensive functions, is an important part of the central nervous system. Morphological and functional changes in astrocyte have been observed in diabetes mellitus, which involve the quantity, the expression of neurotransmitters and relative transporters, the activity of enzyme, the storage of glycogen and the intercellular connection and communication.