Metabonomics analytical technologies and metabolite identification / 国际药学研究杂志

ABSTRACT

In recent years, the metabonomics technologies have been widely used in numerous science fields. The rapid, accurate analysis and identification for a large number of small molecular metabolites is the key of metabonomics studies, which relies largely on the progress in relevant technologies. The development and combination of many technologies, such as nuclear magnetic resonance (NMR), mass spectrometry (MS), chromatography and capillary electrophoresis, make them possible for the wide application of metabonomics. NMR and MS are the most important technical platforms in metabonomics studies. The unambiguous identification of metabolites is the basic task of metabonomics studies. The research progress in metabonomics analytical technologies and metabolite identification is reviewed in this paper.