Study on quality transfer law of Magnoliae Officinalis Cortex in processing based on nine components determination / 中草药

ABSTRACT

Objective: To reveal the scientific connotation of ginger-processed Magnoliae Officinalis Cortex (MOC), and standardize the production process and offer the theoretical base for clinical medication. Methods: This paper studied on quality transfer law of MOC in processing based on the determination of nine chemical components, including syringing, magnocurarine, magnolin B, magnoflorine, magnolin A, honokiol, magnolol, piperitylmagnolol, and β-eudesmol, through controlling factors such as part of sample collection, processing technology, personnel, equipment and environment. Results: The results showed that the content of phenolic components was increased slightly, the content of alkaloids was decreased significantly, and the content of glycosides was decreased, and the content of magnoloside B was decreased significantly in the process of preparation for MOC and ginger-processed MOC. Moreover, there was no significant difference in the content of magnoloside A, syringin, and volatile oil represented by β-eudesmol. Conclusion: This study preliminarily explored the quality transfer law of multi-components in the processing of MOC, and provided reference for the establishment of the quality control system of the crude drug processing technology and improvement of the quality of products.