Network Meta-analysis of five common dressings in the treatment of pressure ulcer / 中国组织工程研究

ABSTRACT

BACKGROUND: There are many kinds of dressings for external use in treating pressure ulcer. Selecting a kind of dressing which is convenient, safe and effective can effectively increase the healing rate of pressure ulcer. OBJECTIVE: To evaluate the effects of five common dressings on the treatment of pressure ulcer. METHODS: A systematic search of Embase, PubMed, VIP, Elsevier, WanFang and CNKI were carried out with an end-point of July 2018. Randomized controlled trials about the therapeutic effects of different dressings on pressure ulcer were collected. All data were screened, extracted and assessed by two researchers independently. The ADDIS 1.16.8 software was adopted for data analysis. RESULTS AND CONCLUSION: A total of 24 randomized control trials (1201 patients) which involved 5 kinds of dressings were included. The results of network Meta-analysis showed that the effect of hydrocolloid dressing and foam dressing were superior to aseptic gauze and vaseline gauze in treating pressure ulcer (P 0.05). Based on the probability ranking table, the therapeutic effects of five kinds of dressl ngs in pressure ulcer were ranked as follows hydrocolloid dressing > foam dressing > hydrogel dressing > sterile gauze > vaseline gauze. Hydrocolloid dressing and foam dressing were superior to the other dressings in the treatment of pressure ulcer.