Effects of physical activity and exercise on metabolic syndrome / 中国组织工程研究

ABSTRACT

BACKGROUND: Metabolic syndrome appeared at older and lower age. Increasing physical activity and active movement can effectively improve insulin sensitivity in patients with metabolic syndrome, regulate lipid and glucose metabolisms, decrease blood pressure and reduce the incidence of metabolic syndrome. OBJECTIVE: To comprehensively review the effect of physical activity and exercise intervention on metabolic syndrome, and to further reveal the positive benefits of physical activity, aerobic exercise and resistance movement to young children and middle-aged and elderly people, so as to provide theoretical and practical reference for effective prevention, mitigation and treatment of metabolic syndrome. METHODS: PubMed, CNKI, and ElsevierSDOL databases were used to search relevant articles with the keywords of “metabolic syndrome, physical activity, exercise” in Chinese and English, respectively. The pathogenesis of metabolic syndrome and the influence of physical activity and exercise on metabolic syndrome were summarized to confirm the included studies eligible for the objectives. RESULTS AND CONCLUSION: (1) Adequate physical activity is an independent protective factor of metabolic syndrome. A healthy lifestyle, such as less sitting and hyperactivity, changing travel mode and increasing housework, can effectively accelerate energy metabolism and improve insulin sensitivity in all groups, reduce the prevalence of metabolic syndrome and each component of the disease. (2) Regular exercise has a significantly positive effect on the prevention and treatment of metabolic syndrome. Aerobic exercise and resistance exercise can reduce the body fat content and insulin resistance and other risk factors. Resistance exercise can increase skeletal muscle content, increase basal metabolic rate and insulin sensitivity, especially control blood sugar. Only aerobic exercise can correct the inflammatory reaction of metabolic syndrome, and has more advantages in reducing body fat and lowering blood pressure. (3) Obesity in children and adolescents is closely related to metabolic syndrome. Physical activity and exercise play a significant role in the prevention and improvement of metabolic syndrome, while the improvement of metabolic syndrome can control obesity in children and adolescents. The survival rate of middle-aged and elderly patients with metabolic syndrome decreased, the risk of cardiovascular and cerebrovascular diseases increased, and the mortality rate increased. Lifestyle change and regular exercise are important measures to prevent and cure the occurrence of metabolic syndrome and cardiovascular and cerebrovascular diseases in the middle-aged and elderly.