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Research progress in miR-138 in tumors / 肿瘤
Tumor ; (12): 1334-1338, 2017.
Artigo em Chinês | WPRIM | ID: wpr-848453
ABSTRACT
microRNA (miRNA, miR) has attracted great interest in recent years. miR-138 is closely related to the occurrence, development and prognosis of different kinds of malignant tumors.Present studies have shown that miR-138 is frequently down-regulated in tumor cells and tissues. Down-regulation expression of miR-138 can promote the proliferation, invasion and metastasis in a variety of malignant tumor cells. Up-regulation expression of miR-138 may play a crucial role in tumor suppression, and enhance sensitivity of tumor cells to radiotherapy and chemotherapy. Therefore, miR-138 can be considered as a biomarker of tumor prognosis, and also one of the tumor therapeutic targets.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Tumor Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Tumor Ano de publicação: 2017 Tipo de documento: Artigo