Research progress in miR-138 in tumors / 肿瘤
Tumor
;
(12): 1334-1338, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-848453
ABSTRACT
microRNA (miRNA, miR) has attracted great interest in recent years. miR-138 is closely related to the occurrence, development and prognosis of different kinds of malignant tumors.Present studies have shown that miR-138 is frequently down-regulated in tumor cells and tissues. Down-regulation expression of miR-138 can promote the proliferation, invasion and metastasis in a variety of malignant tumor cells. Up-regulation expression of miR-138 may play a crucial role in tumor suppression, and enhance sensitivity of tumor cells to radiotherapy and chemotherapy. Therefore, miR-138 can be considered as a biomarker of tumor prognosis, and also one of the tumor therapeutic targets.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Tumor
Ano de publicação:
2017
Tipo de documento:
Artigo
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