Cervical cancer incidence and mortality in 2010-2013 and the mortality trend in last 40 years in Hebei Province / 肿瘤

ABSTRACT

Objective: The aim of this study is to estimate the cervical cancer burden in 2010-201 3 and analyze the mortality trend in the last forty years in Hebei Province, China. Methods: Cancer registry data from 21 cancer registries in Hebei Province were qualified and checked according to the regulations from the National Cancer Registry Center. The pooled data were stratified by age. The incidence and mortality rates were calculated and expressed in 1/100 000. Cervical cancer mortality data during the three periods in Hebei Province were extracted from the national death surveys and calculated. The estimated annual percentage change (EAPC) for the whole period in Cixian County and Shexian County was evaluated using Joinpoint regression model. Results: The estimated numbers of newly diagnosed cervical cancer cases and deaths in 2010-2013 were 21 942 and 5 770, respectively. The crude incidence rate (CIR) was 14.62/100 000; the age-standardized incidence rate using Segi's population standard by WHO (ASIRW) was 10.78/100 000. The crude mortality rate (CMR) was 3.74/100 000; the age-standardized mortality rate using Segi's population standard by WHO (ASMRW) was 2.69/100 000. The ASMRW displayed a decreasing trend in Hebei Province from 1973-1975 to 2010-2013. In Cixian county, the incidence rate decreased with an EAPC of-0.94% from 1988 to 2001. A significant increasing trend was shown from 2001 to 2013, with an EAPC of 10.67%; the mortality rate showed an increasing trend form 1988 to 2013, with an EAPC of 1.03. A similar increasing trend was observed for the incidence and mortality rates in Shexian county in 2000-201 3, with EAPC of 7.04 and 3.63, respectively. Conclusion: Hebei Province experienced a relative heavy burden of cervical cancer. Effective measures should be taken to prevent and control the cervical cancer.