Therapeutic effects of 36 patients with esthesioneuroblastoma and their prognosis / 肿瘤

ABSTRACT

Objective: To study the different treatment policies for patients with esthesioneuroblastoma (ENB) and their prognosis. Methods: Thirty-six ENB patients included 20 males and 16 females at average age of 46 years old (24-74 years). Two patients received single surgery and 2 patients received single radiotherapy. Thirty-two patients received combined therapy, which included surgery plus radiotherapy (n = 14), radiotherapy plus chemotherapy (n = 6), surgery plus radiotherapy and chemotherapy (n = 12). All the patients were followed up for 2-60 months and the median follow-up period was 48 months. Statistic analysis was performed using software SPSS 13. 0. Results: The overall 5-year survival rate was 55.6%. The 5-year survival rates of patients between patients with and without cervical lymph nodal metastasis were statistically significant (P < 0.05). Conclusion: Early detection and combined therapy are important to improve survival rate. Cervical lymph node metastasis is significantly correlated with the prognosis. Radiotherapy plays an important role in the management of the disease.