Relationship between seroma formation after operation of breast cancer with comorbidity of internal diseases and patients' characteristics: A clinical study / 肿瘤

ABSTRACT

Objective: To investigate the relationship between the incidence of postoperative seroma formation and the comorbidity of internal diseases. Methods: Clinical data from 130 patients who underwent breast surgery in the department of breast cancer in our hospital were collected and the seroma formation was observed prospectively. Univariate and multivariate analyses were used to analyze the risk factors related with seroma formation. The difference was compared between the seroma formation group and the control group. Results: Univariate analysis showed that the average of age (59.13 years old vs 51.37 years old, P = 0.002) and body mass index (BMI) (25.33 vs 22.90, P = 0.018) were both significantly higher in the seroma formation group. The incidence of hypertension was higher in the seroma group(30.4% vs 12.1%, P = 0.027). Logistic regression analysis showed that age (OR = 1.065, 95% CI = 1.012-1.116, P = 0.016) and BMI (OR = 1.193, 95% CI = 1.025-1.389, P = 0.023) were independent risk factors for seroma formation. Conclusion: The incidence of postoperative seroma formation after breast surgery was related with age, BMI and comorbidity of internal diseases. The appropriate management during perioperative period may be beneficial for decreasing the incidence of seroma formation.