The expressions of nm-23 and CD44v6 protein in non-small cell lung cancer and their clinical significance / 肿瘤

ABSTRACT

Objective: To study the expressions of nm23 and CD44v6 proteins in non-small cell lung cancer (NSCLC) and their clinical significance. Methods: Expressions of nm23 and CD44v6 proteins were detected in 58 cases with NSCLC by two-step immunohistochemistry. Results: The overall positive rate of nm23 staining was 87.9% (51/58). There was a significant difference between T1-T2 group and T3-T4 group (P 0.05). Conclusion: The expressions of nm23 and CD44v6 correlated with the tumor size, pathological classification, differentiation degree of NSCLC but had no relation with pTNM stage and lymphnode metastasis.