The comparative analysis of AFP and CEA results measured with different methods / 肿瘤
Tumor
;
(12): 490-492, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-849569
ABSTRACT
Objective:
To determine the alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) levels by different methods and make a quality control plan to increase the comparability of the results.Methods:
The serum samples containing different levels of AFP and CEA were collected. External quality control assessment was implemented. The samples were distributed in different laboratories. The participants were requested to perform a conventional assay employed in their laboratories and return their reports in restricted period. The results were classified according to different testing methods and the statistical analysis was performed.Results:
Concerning the qualitative assay, the accordance rate was 100% for AFP-negative, -weak positive, and-positive samples; the accordance rate was 100% for CEA-negative samples, 60% for CEA-weak positive samples, and 85% for CEA-positive samples. Concerning the quantitative assay, the coefficient of variation (CV) was in the range of 9.9%-73.9% for AFP and 11.5%-65.3% for CEA.Conclusion:
There was not better comparability of AFP and CEA results measured with different methods. The better comparability required higher standard of quality control.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Pesquisa qualitativa
Idioma:
Chinês
Revista:
Tumor
Ano de publicação:
2007
Tipo de documento:
Artigo
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