Comparison of the treatment result of laparoscopic surgery via different approaches versus open resection for large renal cell carcinoma / 解放军医学杂志

ABSTRACT

Objective To investigate the efficacy and safety of laparoscopic surgery versus open resection for large renal cell carcinoma. Methods The clinical data of 60 patients with renal tumor who underwent tumor resection by laparoscopic surgery during January 2009 and January 2015 were reviewed. They were divided into two groups (30 each) according to the surgical approach. Patients in group 1 underwent the operation via intraperitoneal approach, and those of group 2 via retroperitoneal approach. Thirty patients who received laparotomic resection of renal tumor served as control group during the same period. The preoperative examination, perioperative data and postoperative recovery were compared among the three groups. Results The preoperative scan showed that there was no statistical difference in tumor location and its relationship with surrounding tissues among three groups (P>0.05). The operative time was significantly longer in the two laparoscopic groups (groups 1 and 2) than in control group, with a statistically significant difference (P0.05). The postoperative duration of hospital stay was shorter in the two laparoscopic groups than that in open surgery group, with a statistically significant difference (P0.05). The operative pathological results showed that the TNM stage was higher in group 1 than in group 2, with a statistically significant difference (P0.05). Conclusion Laparoscopic surgery is safe and feasible for large renal cell carcinoma.