Treatment of multiple sclerosis with mesenchymal stem cells: A worldwide research and outlook / 解放军医学杂志

ABSTRACT

Multiple sclerosis (MS) is the most common neurological disease in young adults, affecting approximately two million people worldwide nowadays. Unfortunately, there was no effective treatment and interventional method for MS at present. Even the current standard treatment consisting of disease-modifying drugs can only alleviate the clinical symptoms of MS, and these drugs may produce serious adverse side effects, and are ineffective in preventing disease progression in many MS patients. Mesenchymal stem cell therapy (MSCT) in animal models and primary clinical trials have shown potential effect consisting of neuroregeneration and immunomodulation. Therefore, the treatment with mesenchymal stem cells (MSCs) may present a promising tool for the treatment of MS patients.