Research advances in natural products targeting diabetic pancreas β cells / 中草药

ABSTRACT

Type 2 diabetes mellitus is a chronic metabolic disease characterized by insulin resistance and dysfunctional pancreatic β cells. The degree of pancreatic β cells dysfunction is positive correlated with the progression of T2DM; Moreover, existing clinical therapeutic drugs for T2DM are unable to prevent β cell dysfunction. Thus, intervention against dysfunctional pancreatic β cells might be a useful therapeutic strategy to remit even cure T2DM. This article summarizes the research progress on natural products targeting pancreatic β cells for diabetic treatment, with view to providing the reference for the research and development of related drugs.