Observation on safety and clinical efficacy of Longqing Tablets in adjuvant treatment of acute epididymitis / 中草药

ABSTRACT

Objective: To explore the safety and clinical efficacy of Longqing Tablets in the adjuvant treatment of acute epididymitis. Methods: A total of 80 cases of acute epididymitis aged from 18 to 40 were randomly divided into control group and observation group. The control group was treated with antibiotics, while the observation group was treated with antibiotics combined with Longqing Tablets (six tablets per time, bid) for 14 d. The clinical efficacy, obvious and effective rate, pain relief time, semen analysis before and after treatment were compared between the two groups. Results: After two weeks of treatment, 28 patients in the observation group were effective, 12 patients were effective, 0 patients were ineffective, the marked efficiency was 70.0%, the total effective rate was 100%. Totally 19 patients in the control group were effective, 18 patients were effective, three patients were ineffective, the marked efficiency was 47.5%, and the total effective rate was 92.5%. The marked efficiency and total effective rate in the observation group were higher than those in the control group, the difference was statistically significant (P 0.05). Two weeks after treatment, the total sperm motility, normal morphological sperm rate and sperm concentration in the observation group were better than those in the control group, and the difference was statistically significant (P < 0.05). The pain relief time of the observation group (51.0 ± 28.5) h was shorter than that of the control group (70.0 ± 23.5) h, and the difference was statistically significant (P < 0.05). Two months after treatment, the scrotal color Doppler ultrasonography showed five cases of epididymal nodules in the observation group and nine cases in the control group. Conclusion: Longqing Tablets are safe and effective in the adjuvant treatment of acute epididymitis. It can effectively relieve pain and promote the decline of inflammation, and has no obvious adverse effect on semen quality. The effect of continuous application is exact, which is helpful to shorten the course of disease, and is worthy of application and promotion.