A new benzophenone from endohydric moss Pogonatum inflexum / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 1291-1293, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-851253
ABSTRACT
Objective:
To study the chemical components of endohydric moss Pogonatum inflexum in order to find new bioactive compounds. Methods The constituents were separated by column chromatographic methods of silica gel, MCI-Gel resin, Sephadex LH-20, and HPLC. The structures were elucidated by spectroscopic data analysis. The cytotoxicity of compounds for HepG2, HL-60, A549, and MCF7 cell line was also evaluated by using MTT method. Results Two compounds were isolated and identified as 2-(4-benzoyl-3-hydroxyphenoxy)-1-(piperidin-1-yl) ethan-1-one (1) and tert-butyl-2-(4-benzoyl-3-hydroxyphenoxy) acetate (2). Conclusion Compounds 1 is a new compound named pogonatone A; Compound 2 is isolated from Polytrichaceae species for the first time; Compound 1 also displays the high cytotoxicity to HepG2 cell line.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2019
Tipo de documento:
Artigo
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