One new diterpenoid alkaloid from roots of Aconitum sinomontanum / 中草药

ABSTRACT

Objective: To study the chemical constituents from the roots of Aconitum sinomontanum. Methods: Silica gel, Sephadex LH-20 column chromatography, high performance liquid chromatography, and other chromatographic techniques were used for separation and purification. The structures were elucidated by physiochemical methods and spectral data. Results: Five compounds were isolated from the 80% ethanol extract in the roots of A. sinomontanum, and their structures were identified as 6β,7β,8β,15α- tetrahydroxy-1α,14α,16β,18β-tetramethoxy-aconitan-19-en (1), delcosine (2), lepenine (3), napelline (4), and kirinine B (5). Conclusion: Compound 1 is a new compound named sinomontanum J. Compounds 2-5 are isolated from A. sinomontanum for the first time.