Chemical constituents from roots of Rosa cymosa / 中草药

ABSTRACT

To study the chemical constituents from the roots of Rosa cymosa. Methods: The chemical constituents were isolated and purified by silica gel chromatography repeatedly from the roots of R. cymosa, and their structures were identified by spectral analysis and chemical Methods:. Results: Sixteen compounds were isolated from the roots of R. cymosa and identified as 2-acetyl tormentic acid (1), 2-oxo-pomolic acid (2), 2α,3α,19α-trihydroxy-olean-12-en-28-O-β-D-glucopyranoside (3), kaji-ichigoside F1 (4), rosamultin (5), 23-hydroxy-tormentic acid (6), arjunetin (7), 2α,3α,19α,23-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (8), 1β, 3α,19α,23-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (9), catechin (10), 3,4-dihydroxyphenylethyl alcohol 8-O-β-D- glucoside (11), 3,4,5-trimethoxyphenyl-1-O-β-apiofuranosyl (1’’→6’)-β-glucoside (12), 4-hydroxy-3-methoxy-1-phenyl-O-(6’- O-galloyl)-β-D-glucopyranoside (13), ethyl gallate (14), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside (15), and 3,4,5-trimethoxy- benzyl-β-D-glucopyranoside (16). Conclusion: Compounds 9, 11-13, 15, 16 were obtained from this genus for the first time, and compounds 3, 9, 11-16 were obtained from this plant for the first time.