Development, measurement, and application of biopharmaceutics classification system for Chinese materia medica / 中草药

ABSTRACT

Biopharmaceutics classification system (BCS) is a research method that scientifically classifies drugs based on its solubility and permeability, which is generally applicable to oral chemical products of single-component. Compared with most western medicines, Chinese materia medica (CMM) has a complex system of multiple components, so BCS has certain limitations in the study of CMM. Based on the scientific framework of BCS, domestic scholars have successively proposed some BCS for CMM. This article reviews the development, determination, and application of BCS for CMM by consulting relevant domestic and foreign literatures, in order to lay a reference for the in-depth research of BCS for CMM.