Research progress on chemical constituents and biological activities of Wikstroemia indica / 中草药

ABSTRACT

Wikstroemia indica as a Chinese herbal medicine, belonging to family Thymelaeaceae, was the root and root bark of the plant. Studies found that W. indica had acids, alcohols or esters, quinones, steroids, coumarins, lignans, flavonoids, terpenes, diarylheptanes, and fat-soluble ingredients, and has the effects of antibacterial, anti-virus, cytotoxic, and anti-inflammatory activities etc. The contents of coumarins, flavonoids, quinines, and lignans were measured and applied quality evaluation. In addition, as a toxic Chinese herbal medicine, the toxicity of W. indica could be reduced by processing methods, so further research is needed to confirm the relationship between the compound and its pharmacological activity. In this paper, the researches from 2010 to 2017 on chemical constituents, biological activities, and components detection of W. indica were collected and summarized, aiming to provide reference for further research and development on W. indica.