Study on chemical constituents from roots of Lycium chinense / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 1007-1012, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-852131
ABSTRACT
Objective:
To study the chemical constituents from the roots of Lycium chinense.Methods:
The compounds were isolated and purified by silica gel, ODS and Sephadex LH-20 chromatography in addition to preparative-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analysis.Results:
Twelve compounds were isolated from the EtOAc fraction of the root of Lycium chinense and identified as grossamide K (1), grossamide (2), dihydrogrossamide (3), cannabisin H (4), 1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,4-dihydroxyphenyl)-N1,N2-bis [2-(4-hydroxyphenyl)ethyl]-2,3-naphthalene dicarboxamide (5), cannabisin D (6), (1,2-trans)-N3-(4-acetamidobutyl)-1-(3,4-dihydroxyphenyl)-7-hydroxy-N2-(4-hydroxyphenethyl)-6,8-dimethoxy- 1,2-dihydronaphthalene-2,3-dicarboxamide (7), cannabisin F (8), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxyphenethyl)amino]-3-oxopropyl} phenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-acetamidobutyl)acrylamide (9), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxylphenethyl) amino]-3-oxopropyl}phenyl)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-(4-hydroxyphenethyl)acrylamide (10), (+)-lyoniresinol-3α-O-β-D- glucopyranoside (11), and (−)-lyoniresinol-3α-O-β-D-glucopyranoside (12).Conclusion:
Compound 3 is a new natural product. Compounds 1, 2, and 4—8 are isolated from this plant for the first time.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2018
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS