Applications progress on spectrum-effect relationship in study of Chinese materia medica / 中草药

ABSTRACT

The study of spectrum-effect relationship is one effective method according to the pharmacodynamic material basis and mechanism of action of Chinese materia medica (CMM). The first step is to adopt different modern analysis methods to obtain the compound information of CMM, secondly choose proper animal model to evaluate the pharmacological activity, and then combine two kinds of information mentioned above to find out the main effective substance based on the results of statistical methods. Nowadays, the study of spectrum-effect relationship is widely used in many different aspects. In this article, three different applications of spectrum-effect relationship were mainly summarized, including the study of the quality assessment of CMM, the study of extraction and purification method of CMM and the study of processed CMM, in order to provide reference for the further study of CMM.