Phenolic constituents of Ledum palustre and their anti-oxidant activity / 中草药
Chinese Traditional and Herbal Drugs
; (24): 4394-4398, 2017.
Article
em Zh
| WPRIM
| ID: wpr-852411
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WPRO
ABSTRACT
To study the chemical constituents of Ledum palustre. Methods Compounds were isolated from n-hexane fraction in the ethanol extract from L. palustre by silica gel column chromatography and HPLC. The structures of the chemical constituents were identified by analysis on their spectral data. Results Fourteen compounds were isolated from EtOAc fraction in the ethanol extract from L. palustre and identified as resveratorol (1), moracin M (2), catechin (3), epicatechin (4), scopoletin (5), esculetin (6), fraxetin (7), 5-hydroxy-2methoxybenzoic acid (8), fraxidin (9), 2α,3α-epoxy-5,7,3’,4’-tetrahydroxyflavan-(4β-8)-epicatechin (10), 2α,3α-epoxy-5,7,3’,4’-tetrahydroxyflavan-(4β-8-catechin) (11), cleomiscosin A (12), cleomiscosin C (13), and isofraxoside (14). Conclusion Compounds 1, 2, and 8-13 are obtained from the plants of Ledum L. for the first time. Compounds 3, 4, 6, 7, 10, and 11 had significant anti-oxidative activities.
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WPRIM
Idioma:
Zh
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2017
Tipo de documento:
Article