Screening of transdermal enhancer of naringenin in Premna fulva extract / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 3366-3369, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-852592
ABSTRACT
Objective:
To screen the best transdermal enhancers of naringenin in Premna fulva extract.Methods:
Using abdominal skin of rats as experimental barrier, the in vitro percutaneous absorption experiment was established by modified Franz diffusion cell method. The cumulative infiltration and permeation rate of naringenin in three different penetration enhancers were determined by HPLC.Results:
The borneol, menthol, and azone could enhance transdermal absorption of naringenin in different degree. Several penetration enhancers were increased in the following order borneol > menthol > azone. The average percutaneous rate of naringenin was 0.136 8 mg/(cm2∙h), using 5% borneol as penetration enhancer.Conclusion:
The 5% borneol is an effective transdermal enhancer for naringenin in P. fulva extract.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2017
Tipo de documento:
Artigo
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