Chemical constituents of Anoectochilus roxburghii / 中草药

ABSTRACT

Objective: To study the chemical constituents of Anoectochilus roxburghii. Methods: The chemical constituents of A. roxburghii were separated and purified by silica gel column chromatography, recrystallization, macroreticular resin, polyamide resin, ODS C18, and HPLC. Compound structures were identified by the spectral data and the physical and chemical properties. Results: From this plant, nineteen compounds were obtained, such as (22E, 24ξ)-24-isopropenyl-22-dehydrocholesterol (1), anoectosterol (2), stigmasterol (3), β-sitosterol (4), hircinol (5), moscatin (6), 5, 3'-dyhydroxy-3, 7, 4'-trimethoxyflavone (7), linoleic acid (8), 8, 9-epoxyheptadeca-1, 11, 14-triene (9), acetovanillone (10), parahydroxybenzaldehyde (11), parahydroxyacetophenone (12), 5-hydroxy-3', 4', 7-trimethoxyflavonol-3-O-β-D-rutinoside (13), isorhamnetin-3-O-robinobioside (14), β-adenosine (15), isorhamnetin-3-O-β-gentiobioside (16), loroglossin (17), corchoinoside C (18), and parahydroxybenzylalcohol (19). Conclusion: Compounds 1, 16, and 19 are isolated from Orchidaceae for the first time; Compounds 5, 6, 7, 10, and 12 are isolated from Anoectochilus Bl. for the first time; Compounds 9, 15, and 18 are isolated from this plant for the first time.