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Isolation and identification of metabolites in rat urine after ig administration of calycosin-7-O-β-D-glucopyranoside / 中草药
Chinese Traditional and Herbal Drugs ; (24): 2382-2384, 2017.
Artigo em Chinês | WPRIM | ID: wpr-852704
ABSTRACT

Objective:

To study the metabolites from rats urine after ig administration of calycosin-7-O-β-D-glucopyranoside.

Methods:

The constituents were isolated and purified by preparative liquid chromatographic technique, and the structures were identified by spectroscopic analyses including ESI-MS, NMR, and 2D-NMR.

Results:

Five metabolites were isolated from rats urine after ig administration of calycosin-7-O-β-D-glucopyranoside. They were identified as calycosin (M1), 3', 4', 7-trihydroxyisoflavone (M2), daidzein (M3), calycosin-3'-O-β-D-glucuronide (M4), and calycosin-3'-O-β-D-glucuronide methyl ester (M5).

Conclusion:

M5 is a new compound.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico Idioma: Chinês Revista: Chinese Traditional and Herbal Drugs Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico Idioma: Chinês Revista: Chinese Traditional and Herbal Drugs Ano de publicação: 2017 Tipo de documento: Artigo