Study on fingerprint analysis of Xihuang Pills by HPLC-ELSD / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2219-2224, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-852743
ABSTRACT
Objective:
To establish the quality evaluation of fingerprints of Xihuang Pills by HPLC-ELSD.Methods:
The chromatography conditions were defined as waters C18 column (250 mm × 4.6 mm, 5 μm); Mobile phase was methanol-0.5% acetic acid, gradient elution; temperature of column was set at 30℃. The ELSD conditions were as follows the temperature of drift tube was 45℃, the gas speed was 1.5 L/min. Ten batches of Xihuang Pills samples were analyzed for similarity analysis (SA), hierarchical clustering analysis (HCA) and principle component analysis (PCA).Results:
The chromatographic fingerprint was completed with 25 recognizable peaks, and the samples with great differences and the compounds with greater impact on the quality were obtained through HCA and PCA.Conclusion:
HPLC fingerprint combining with pattern recognition could reflect the intrinsic quality to provide a scientific basis for the quality control of Xihuang Pills.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2017
Tipo de documento:
Artigo
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