Optimization of processing technology of Hemsleya omeiensis by orthogonal design and central-composite design-response surface methodology / 中草药

ABSTRACT

Objective: To optimize the processing technology of Hemsleya omeiensis processed by licorice juice. Methods: HPLC was employed to determine the content of hemslecin A.Taking content of hemslecin A as index, the orthogonal test was adopted to optimize the covered moistening time, drying-time, and processing temperature. And the central composite design-response surface methodology (CCD-RSM) was adapted to optimize moistening time and drying-time further. Results: The optimum processing technology of H. omeiensis by the orthogonal test was covered moistening time of 7 h, drying-time of 12 h, and processing temperature at 80℃. The optimum processing technology by CCD-RSM was covered moistening time of 7.48-8.56 h, drying-time of 12.06-13.12 h, and processing temperature at 80℃. Conclusion: The experimental design method is precise and the data are reliable with the model. It is the first time that H. omeiensis is processed with licorice juice. Besides, it establishes the processing technology of H. omeiensis and provides a theoretical basis for the processing technology of H. omeiensis with licorice juice.