Chemical constituents from Zhuang medicine Sauropus rostratus (II) / 中草药

ABSTRACT

Objective: To study the chemical constituents of Zhuang medicine Sauropus rostratu. Methods: The compounds were isolated and purified by silica gel, polyamide, MCI, and Sephadex LH-20 chromatography. The structures of the compounds were identified on the basis of chemical and spectral methods. Results: Nineteen compounds were isolated from 75% ethanol extrct of S. rostratu and identified as n-triacontanol (1), 2,4-di-tert-butylphenol (2), β-sitosterol (3), daucosterol (4), 3,6-anhydro-2-deoxy- D-arabino-hexono-1,4-lactone (5), niacinamide (6), scopoletin (7), 3β-hydroxy-26α,27β-arbor-13(18)-ene-24-carboxylic acid (8), 2R*,3R*,5S*-trihydroxy-6R*-nonadecyltetrahydropyran-4-one (9), emodin (10), protocatechuic acid (11), 2,3-dideoxy-D-erythro- hex-2-enono-1,4-lactone (12), caffeic acid (13), 3-acetrlc-affeic acid (14), quercetin (15), D-galactose (16), mannitol (17), aurantiamide acetate (18), and kaempferol (19). Conclusion: Compound 8 is a new compound named sauropurostratic acid, and compounds 2,5-14,and 16-18 are isolated from this plant for the first time.