Fragmentation pathways of six aconitine alkaloids using HPLC-Q-TOF-MS technology / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2827-2831, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-853332
ABSTRACT
Objective:
To study the fragmentation pathways of six aconitine-type alkaloids (aconitine, hypaconitine, mesaconitine, benzoylaconitine, benzoylhypaconitine, and benzoylmesaconitine) in mass spectra (MS).Methods:
The samples were analyzed by liquid chromatography-tandem quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS).Results:
In positive mode, The typical fragmentation pathways of the six aconitine-type alkaloids were mainly continuous loss of CH3OH and H2O. The characteristic fragmentation pathway of diester-diterpene type aconitine was losing an acetic acid molecule from C-8 position; However this fragmentation could not be observed in MS of mono-ester aconitine alkaloids.Conclusion:
The study on fragmentation pathways could be adopted for the structural identification of the six aconitine-type alkaloids.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2016
Tipo de documento:
Artigo
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