Chemical constituents from leaves of Adinandra nitida / 中草药

ABSTRACT

Objective: To study the chemical constituents from the leaves of Adinandra nitida. Methods: The chemical constituents of the plant were isolated and purified by column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral data. Results: Eleven triterpenoids, two diterpenoids, and two steroids were obtained and determined to be ursolic acid (1), 18-hydroxyursolic acid (2), 2α,3α-dihydroxyursolic acid (3), 3α,19α-dihydroxyursolic acid (4), euscaphic acid (5), 3β,19α,23-trihydroxyursolic acid (6), 2α,3α-dihydroxyursolic acid-28-O-β-D-glucopyranoside (7), kajiichigaside F1 (8), oleanolic acid (9), arjunetin (10), betulinic acid (11), cassipourol (12), α-tocopherol (13), daucosterol (14), and β-sitosterol (15). Conclusion: Compounds 1-4, 6, 7, 9, and 11-13 are obtained from the leaves of A. nitida for the first time.