Chemical constituents from Notopterygium incisum / 中草药

ABSTRACT

Objective: To investigate the chemical constituents of Notopterygium incisum. Methods: The chemical constituents were isolated by silica gel column chromatography, HPLC, and Sephadex LH-20 column chromatography. Their structures were identified on the basis of spectral data analysis. Results: Fourteen compounds were isolated and identified as 7-hydroxycoumarin (1), 5,7-dimethoxycoumarin (2), nodakenetin (3), bergaptol (4), bergapten (5), isopimpinellin (6), byakangelicin (7), (+)-cis-khellactone (8), (-)-trans-khellactone (9), p-hydroxypenehtyl anisate (10), 5-methoxy-8-hydroxypsoralen (11), ferulic acid (12), isoimperatorin (13), and isopsoralen (14). Conclusion: Compounds 2, 7-9, and 11 are isolated from the plants of Notopterygium H. Boiss. for the first time.