Chemical constituents from Incarvillea sinensis var. przewalskii / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the whole plant of Incarvillea sinensis var. przewalskii, and a systematically phytochemical investigation was carried out. Methods: The chemical constituents were isolated by column chromatographies, such as silica gel and Sephadex LH-20 columns as well as semi-preparative HPLC, and their structures were determined on the basis of MS, NMR spectroscopic analyses, and/or comparison with literature data. Results: Thirteen compounds, including alkaloids and phenylethanoid glycosides, were isolated from the 80% ethanol extract of the whole plants. Their structures were elucidated as p-butoxyl-salidroside (1), incasine C (2), incarvillateine (3), 7-hydroxyskytanthine (4), incarvilline (5), phenethylalcohol glucoside (6), martynoside (7), acteoside (8), deacylisomartynoside (9), decaffeoy1acteoside (10), carceorioside B (11), salidroside (12), and deacylacteoside dimethyl ether (13). Conclusion: Compound 1 is a new one, and the other compounds are isolated from this species for the first time.