Survey of active components in commonly-used Chinese materia medica injections and related Chinese materia medica for cardiovascular disease / 中草药

ABSTRACT

To summarize the active components in commonly-used Chinese materia medica (CMM) injections and related CMM for cardiovascular disease, and provide the reference for the effective treatment of cardiovascular disease. We searched CNKI, Wanfang Data, PubMedand, and the reference lists of identified articles (from initial to September 1, 2014), and reviewed the literature. The commonly-used CMM injections for cardiovascular disease involve 15 kinds of injection, including Shenfu Injection, Shenmai Injection, Ciwujia Injection, Danhong Injection, etc. Three prescriptions originated from classical prescriptions but others were from the result of clinical and research. The CMMs in these prescriptions were all less in number, single flavor accounted for 60%, the maximum was three herbs. These injections mainly aimed at heart blood stasis syndrome, with many pharmacological effects of protection on cerebral ischemia-reperfusion damage, anti-thrombosis, anti-oxidants, and expansion of coronary artery. The most commonly-used CMMs were Salvia Miltiorrhiza Radix, Ginseng Radix et Rhizoma Rubra, and Carthami Flos. The kinds of active components included flavonoid, saponin, quinones, etc. This article provides a basis for the effective treatment of cardiovascular disease.