Chemical constituents from Dianthus superbus / 中草药

ABSTRACT

To investigate the chemical constituents of Dianthus superbus. The chemical constituents were isolated from 95% alcohol extract of D. superbus by silica gel column chromatography, Sephadex LH-20 column chromatography, and HPLC. Their chemical structures were elucidated on the basis of 1D NMR and ESI-MS spectroscopic analyses. Nine compounds including three flavanoids, two sterols, three triterpenes, and one γ-lactone were isolated. Their structures were identified as 5-hydroxy-7, 3', 4'-trimethoxyflavanone (1), 5, 3'-dihydroxy-7, 4'-dimethoxyflavanone (2), 5, 4'-dihydroxy-7, 3'-dimethoxyflavanone (3), β-spinasterol (4), sterculin A (5), (24R)-cycloart-25-ene-3β, 24-diol (6), (24S)-cycloart-25-ene-3β, 24-diol (7), stigmast-7-en-3β-ol (8), and hydoxydihydrobovolide (9). Conclusion All the compounds (1-9) are isolated from D. superbu for the first time.