Chemical constituents from Incarvillea delavayi / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the whole plant of Incarvillea delavayi. Methods: The whole plant of I. delavayi was extracted by 90% ethanol. Various chromatography methods were employed to separate the chemical constituents, and the structures were identified by comprehensive spectroscopic analysis. Results: Fourteen compounds, including cyclohexanethanoids, monoterpene alkaloids, and triterpenoids, were obtained from the 90% ethanol extract of I. delavayi. Their structures were identified as 5-hydroxyethyl-6-hydroxyl-3-methyl benzofuran (1), cleroindicin B (2), 3,4,5-trimethoxyl benzoic acid ethyl ester (3), 3,4,5-trimethoxyl benzoic acid methyl ester (4), 6-hydroxyl dihydrobenzofuran (5), 2-(4'-ethoxyphenyl)-ethanol (6), tecomine (7), (+)-epidihydrotecomanine (8), 5-hydroxy skytanthine (9), δ-skytanthine (10), isoincarvilline (11), mairine B (12), coelobillardierine (13), and 3β-acetyl oleanolic acid (14). Conclusion: Compound 1 is identified as new compound and named as delavayol A, while compounds 3-6, 9-11, and 13 are isolated from the titled plant for the first time.