A Case of Osteomalacia with Long Term Carbamazepine Therapy / 대한내분비학회지
Journal of Korean Society of Endocrinology
;
: 286-290, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-85451
ABSTRACT
Anticonvusant therapy with any of several agents, especially phenytoin, phenobarbital, and primidone causes disturbances in bone mineral metabolism. Anticonvulsants stimulate the hepatic microsomal mixed-oxidase enzymes and hence increase the rate of clearance of vitamin D and its metabolism. The severity of clinical manifestations in any given individual appears to be a function of the combined effects of variety of factors including drug type and total drug dose, dietary vitamin D intake, sunlight exposure, and physical activity level. We report a case of osteomalacia associated with long term carbamazepine therapy in a 21-year-old male with less exposure to sunlight.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteomalacia
/
Fenobarbital
/
Fenitoína
/
Primidona
/
Luz Solar
/
Vitamina D
/
Carbamazepina
/
Metabolismo
/
Atividade Motora
/
Anticonvulsivantes
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
2000
Tipo de documento:
Artigo
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